Man on the Moon was shot over three days in the desert, at Lancaster in the Antelope Valley area of California, in October 1992. Michael Stipe, attired in a cowboy hat, walks along a desert road. He leaps onto a passing truck, driven by Bill Berry, and hitches a ride to a truck stop where Peter Buck is tending bar and Mike Mills is shooting pool. Berry trades his truck seat for a bar stool, and along with a few of the other customers (in the shooting they used both actors and non-actors), sings along during the choruses. After finishing his order of fries, Stipe leaves and walks off into the dusk. In the background on a small television set in the truck stop, various footage of Andy Kaufman can be seen showing.
This video was ranked #41 on Rolling Stone magazine's The 100 Top Music Videos.