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Open Your Heart was shot at Echo Park in Los Angeles, California, and Madonna portrays an exotic dancer who befriends a young boy, played by a child actor/dancer Felix Howard. The video was also nominated for three MTV Video Music Awards. The video has been described as paying homage to Liza Minnelli as the character Sally Bowles in the Bob Fosse-directed film musical Cabaret.

Madonna also decided to use one of her favorite artists' work in the video, Tamara De Lempicka. Groups were outraged at the use of a minor entering a strip club and sharing a kiss with Madonna at the end. Madonna described the video as a statement about innocence.

This video was ranked #37 on VH1's 50 Sexiest Video Moments.

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